PupFlex+PupFlex+PupFlex+PupFlex+PupFlex+PupFlex+PupFlex+help your dog experience joint comfort and mobility with advanced bioavailability from biopupTM! directions for use: < 25lbs 1 chew daily, 25-75lbs 2 chews daily, >75lbs 3 chew daily

Joint Health & Mobility Soft Chews For Dogs

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Supports cartilage structure & mobility

Helps reduce stiffness and discomfort

Greater efficacy than Glucosamine & Chondroitin

6 Clinically proven ingredients

Choose your dog's weight

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$63.00

/2 months

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Supports Joint Mobility

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Reduces Stiffness Discomfort

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Enhances Cartilage Health

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Clinically Proven Formula

Real Dog Owners. Real Results. Real Stories

Rated 4.5 out of 5 by over 1,000+ pet parents like you.

Bag of PupFlex+ soft chews for dogs supporting joint health and mobility.

5 Powerful Reasons Every Pet Parent Needs to Try PupFlex+ for Their Dog’s Joint Health

Watching your beloved pup struggle with stiff joints and reduced mobility is heartbreaking. Every pet parent wants their furry companion to live an active, pain-free life—but finding a truly effective joint supplement can feel impossible.

That’s why thousands of dog owners are turning to PupFlex+, a premium joint support supplement designed to promote long-term mobility, flexibility, and comfort.

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Helps With:

Powerful Antioxidant Protection

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Promoting Mobility & Flexibility

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Joint Pain and Stiffness

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Decreasing Inflammation

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Cushioning and Lubricating Joints

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Supporting Cartilage Structure

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Powerful Antioxidant Protection

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Promoting Mobility & Flexibility

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Joint Pain and Stiffness

|

Decreasing Inflammation

|

Cushioning and Lubricating Joints

|

Supporting Cartilage Structure

|

Powerful Antioxidant Protection

|

Promoting Mobility & Flexibility

|

Joint Pain and Stiffness

|

Decreasing Inflammation

|

Cushioning and Lubricating Joints

|

Supporting Cartilage Structure

|

Powerful Antioxidant Protection

|

Promoting Mobility & Flexibility

|

Joint Pain and Stiffness

|

Decreasing Inflammation

|

Cushioning and Lubricating Joints

|

Supporting Cartilage Structure

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1. Clinically Proven Ingredients for Maximum Joint Support

Not all joint supplements are created equal. PupFlex+ stands out because it’s packed with scientifically backed ingredients, including UC-II® (Undenatured Type II Collagen), CurcuVet® (Curcumin Phytosome®), ApresFlex® (Boswellia Serrata), Antarctic Krill Omega-3 and AstaReal® Astaxanthin.

These powerful actives work synergistically to reduce inflammation, rebuild cartilage, and improve joint function—helping dogs of all breeds, sizes, and ages stay active and pain-free.

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2. Fast-Acting Formula – See Results in Just 3 Weeks

Many pet owners grow frustrated with supplements that take months to show results, if they work at all. But with PupFlex+, most dogs experience noticeable improvements in mobility within just 3-4 weeks!  This rapid relief is thanks to high-bioavailability of active ingredients that get to work soothing stiff joints, reducing pain and discomfort, and enhancing flexibility faster than traditional Glucosamine based supplements.

3. Ultimate Joint support and protection for effortless movement

UC-ll® Collagen supports cartilage structure, reduces joint pain by 57% in 30 days, promotes healthy mobility and flexibility. CurcuVet® ( Curcumin Phytosome) reduces joint discomfort and inflammation 29 times more effectively than other curcumin extracts. ApresFlex®( Boswellia Serrata AKBA) relieves joint pain and supports structural integrity of joints and connective tissue. Antarctic Krill is a source of highly bioavailable Omega-3 fatty acids.

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4. Powerful Antioxidant Protection to Combat Joint Damage

Inflammation and oxidative stress are major culprits behind joint deterioration. PupFlex+ includes AstaReal® Astaxanthin, one of the most potent antioxidants on the planet, to fight off damaging free radicals and slow down joint wear and tear.

This means stronger, healthier joints for years to come, giving your pup the comfort and mobility they deserve.

5. Perfect for Every Dog – From Playful Puppies to Aging Seniors

Whether you have a high-energy pup, a working dog, or a senior companion slowing down with age, PupFlex+ is formulated to support their joint health at every life stage.

Early supplementation can help maintain flexibility and prevent future issues, while older dogs benefit from reduced stiffness and improved comfort—making every tail wag a little easier.

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The #1 Choice For Pet Parents

See Why 1.4 million customers trust Biopup

Effective joint support

Our oldest dog Molson (7) was diagnosed with arthritis and once he started taking these, we saw a noticeable difference in his mobility!

- Christa

You NEED to try this supplement

Our high energy border collie is turning eight this year and we want to make sure we are taking the best care of his joints that we can. We had been looking for a joint chew with krill and we have been really happy with PupFlex.

- Arlo

Excited for this

PupFlex+ made a big difference for my dog’s mobility. He used to show some stiffness after long walks, but after a few weeks of using these chews, he’s much more active and moves with ease.

- Kamila S.

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Crafted with Premium, Clinically Proven Ingredients

Formulated with the highest-quality, science-backed ingredients to support your dog’s joint health and mobility.

Committed to Premium Quality

Our team of scientific experts ensures every step of our product innovation meets the highest standards.

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Third-Party Lab Tested

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90 Days Satisfaction Gurantee

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Manufactured In USA

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GMP Certified

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Non-GMO

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Vet Approved

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Frequently Asked Questions

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