200+  5-Star Reviews

Pioneering the new science of joint health.

Vet approved joint health supplement with UC-ll® Collagen clinically shown to improve mobility and reduce discomfort by 62% in just 30 days*.

Shop Now — Up to 55% OFF

90-Day Satisfaction Guarantee | Made in the USA

* UC-II Combo Supplement; UC-II Mechanism of Action; UC-II Anti-Inflammatory Effects; UC-II Pain Reduction, UC-II Immune Suppression, UC-II vs. Pharma, UC-II Review

PupFlex+ Supports

Joint Cushioning and Lubrication
PupFlex+ helps maintain comfortable joint movement by supporting natural cushioning and lubrication, allowing your dog to stay active and move freely.
Normal Inflammatory Response
Contains key ingredients that help support a balanced inflammatory response associated with daily activity and exercise.
Cartilage and Connective Tissue Health
Formulated with ingredients that help nourish and support healthy cartilage structure—promoting flexibility, resilience, and ease of motion.
Mobility and Flexibility
Supports overall joint mobility and flexibility to help dogs of all ages stay agile, energetic, and ready for play.
Joint Cushioning and Lubrication
PupFlex+ helps maintain comfortable joint movement by supporting natural cushioning and lubrication, allowing your dog to stay active and move freely.
Normal Inflammatory Response
Contains key ingredients that help support a balanced inflammatory response associated with daily activity and exercise.
Cartilage and Connective Tissue Health
Formulated with ingredients that help nourish and support healthy cartilage structure—promoting flexibility, resilience, and ease of motion.
Mobility and Flexibility
Supports overall joint mobility and flexibility to help dogs of all ages stay agile, energetic, and ready for play.

Made with Love, Backed by Science.

Learn about our active ingredients, bioavailability, & the research that went into creating PupFlex+

With a synergetic complex of clinically proven ingredients that have never been used in combination before, PupFlex+ works faster and is more effective than common Glucosamine supplements.

The Science Our Ingredients

Who is PupFlex+ for?

Active dogs, senior dogs, young dogs, performance pups, and working dogs! Support your dog’s joints throughout their entire life. Early supplement administration can maintain and improve mobility, flexibility, and agility throughout your pup’s lifetime.

Benefits

  • Supports healthy joint function & flexibility
  • Supports joint cartilage and connective tissue structure
  • Supports normal inflammatory response for joint comfort
  • Helps decrease stiffness by promoting joint cushioning & lubrication
  • Provides powerful antioxidant protection
  • May improve athletic performance & recovery