SCIENCE & INGREDIENTS

Better Ingredients for Better Mobility

PupFlex+® is unique in that it contains the most studied, clinically proven nutraceuticals in one single product. Help your dog feel better by maintaining & restoring normal mobility. PupFlex+® soft chews are made with all-natural, and Non-GMO ingredients.

PupFlex+ dog chews packaging with blue geometric dog design and health support text.

The PupFlex+ Solution

High Bioavailability • Multi-Pathway Support • Fast-Acting Comfort • Complete Joint Health

Made With Standards You Can Trust

BioPup™ is made in the USA with rigorous quality standards, third-party testing, and veterinary review behind every formula.

NASC Quality Seal

Made by a company that meets rigorous NASC quality, labeling, and testing standards.

VetEvaluated® Certified

Reviewed through a veterinarian-founded certification program focused on pet product quality and safety.

Manufactured to GMP Standards

Produced under strict manufacturing procedures for quality and consistency.

Third Party Lab Tested

Independently tested to verify quality, purity, and label accuracy.

INGREDIENTS & SCIENCE

Changing the Narrative on Canine Joint Health

PupFlex+® is a science-driven supplement that covers multiple bases for your dog’s joint health: cartilage structure support, antioxidant protection from free radicals damage, healthy inflammatory response, joint fluid viscosity, pain, and discomfort management to support free range of motion.

A man holds an English bulldog on his lap and a pouch of PupFlex dog supplements.

Dr. Firstname Lastname, DVM

Understanding the Impact

Factors such as age, normal wear & tear from everyday activities, and cartilage microtraumas from running & jumping can take a toll on a dog's health, and good nutrition alone isn't the solution. By most estimates, 40% of all dogs—regardless of age or breed, are affected by joint and mobility discomfort. It’s possible that 80% of dogs will show x-ray evidence of the joint problems in their lifetime, which makes mobility and joint discomfort the most common issue that dogs suffer from.

Unfortunately, mobility issues can progress over time. Preventing development by maintaining a healthy body weight with a good diet and appropriate exercise, and administering a high-quality protective joint supplement such as PupFlex+®, is the best way to keep your dog’s joints healthy.

THE PUPFLEX+® SOLUTION

We Use Better Active Ingredients for a Reason.

The ingredients used in PupFlex+® are more bioavailable, backed by science, and beneficial for dog’s health. We found that supplements currently on the market don’t focus on bioavailability, active ingredient composition, quality of ingredients, or proper dosing. We had to do something different!

THE PUPFLEX+® SOLUTION

We Use Better Active Ingredients for a Reason.

The ingredients used in PupFlex+® are more bioavailable, backed by science, and beneficial for dog’s health. We found that supplements currently on the market don’t focus on bioavailability, active ingredient composition, quality of ingredients, or proper dosing. We had to do something different!

A close-up, macro shot of a golden, viscous liquid with small bubbles suspended within it on a white background.

Undenatured Type II Collagen

UC-II®

NATURALLY DERIVED

Undenatured Type II Collagen supports cartilage structure, mobility, and flexibility. Clinical studies proved UC-II to be over 50% more effective than glucosamine for joint health.

SCIENTIFIC STUDY

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A piece of turmeric root next to a pile of vibrant yellow ground turmeric powder.

Curcumin Phytosome®

CurcuVet®

FROM TURMERIC

Curcumin Phytosome® helps reduce inflammation and occasional discomfort. It is 29 times more potent & bioavailable than most curcumin extracts.

SCIENTIFIC STUDY

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A close-up, microscopic view of a translucent krill showing its large black eyes and red internal organs.

Antarctic Krill

QrillPet®

SUSTAINABLY SOURCED

Antarctic Krill is a source of highly bioavailable krill oil from dried krill and the source of anti-inflammatory Omega 3 fatty acids DHA and EPA. Studies showed that krill oil provided improved absorption of omega-3 fatty acids compared to fish oil.

SCIENTIFIC STUDY

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A close-up of a gnarled branch with clusters of small, light green, unripe fruit against a white background.

Boswellia Serrata AKBA Extract

ApresFlex®

PLANT BASED

Boswellia Serrata AKBA extract. It is clinically proven to ease joint discomfort and inflammation, supports structural integrity of joints and connective tissue. Shown to reduce joint pain in 5 days in human clinical trials. AprèsFlex, in combination with CurcuVET®, can protect against the degradation of collagen, which is an important component of connective tissue.

SCIENTIFIC STUDY

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Astaxanthin

AstaReal®

RED ALGAE EXTRACT

Astaxanthin is the king of carotenoids. It is a powerful antioxidant that is 6000 times more potent than vitamin C, 550 times better at fighting free radicals than vitamin E, and 600 times stronger than CoQ10. AstaReal® Astaxanthin supports joint and muscle health with protection from free radicals and nitrous oxide. Additional benefits: Supports heart, brain and eyes health, improves mitochondrial function.

SCIENTIFIC STUDY

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A clear, viscous liquid pours from a glass bottle, with a single drop in the background.

Hyaluronic Acid

High Molecular Weight

NATURALLY DERIVED

High molecular weight Hyaluronic Acid supports joint flexibility and viscosity of synovial fluids. It cushions and lubricates the joints to promote free range of motion.

SCIENTIFIC STUDY

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