

PupFlex+
Joint Health & Mobility Soft Chews For Dogs
Joint Health & Mobility Soft Chews For Dogs
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PupFlex+ is the science backed health supplement your dog’s joints have been waiting... read more
PupFlex+ is the science backed health supplement your dog’s joints have been waiting for. We combine six breakthrough ingredients that work like a specialized repair team for your dog's joints—each one chosen because it tackles joint health from a different angle, creating results that outdated supplements simply can't match. The difference? PupFlex+ doesn’t mask discomfort. It helps to rebuild what time and activity have worn down.
Notice joint comfort improvements in just 30 days*
Watch your dog rediscover their natural mobility
Supports normal inflammatory response to assist with stiffness & discomfort
Promotes healthy joint cartilage & connective tissue. Doesn't just mask symptoms
Uses nature's joint oils, Antarctic krill and omega-3s, to lubricate joints
Recommended, tested, and certified by VetEvaluated® veterinarians
More effective than outdated Glucosamine & Chondroitin supplements
Notice joint comfort improvements in just 30 days*
Watch your dog rediscover their natural mobility
Supports normal inflammatory response to assist with stiffness & discomfort
Promotes healthy joint cartilage & connective tissue. Doesn't just mask symptoms
Uses nature's joint oils, Antarctic krill and omega-3s, to lubricate joints
Recommended, tested, and certified by VetEvaluated® veterinarians
More effective than outdated Glucosamine & Chondroitin supplements


Active Ingredients:
QrillPetTM Dried Antarctic Krill | 750 mg |
Providing Omega-3 Fatty Acids | 30 mg |
EPA | 16 mg |
DHA | 9 mg |
Astaxanthin | 0.06 mg |
UC-ll® (Undenatured Type II Collagen) |
20 mg |
CurcuVET® (Curcuma longa extract (root) Phospholipid Complex from Sunflower) | 75 mg |
AprèsFlex® Boswellia serrata (gum resin) extract [std. to 20% 3-O-acetyl-11-keto-ദ-boswellic acid (AKBA)] | 25 mg |
AstaReal® Astaxanthin (Haematococcus pluvialis algae extract) |
1 mg |
Hyaluronic Acid (High molecular weight) |
10 mg |

*Individual results may vary and can take up to 90 days of daily supplementation.
Helps With:












Who is PupFlex+ for?
Active dogs, senior dogs, young dogs, performance pups, and working dogs! Support your dog’s joints throughout their entire life. Early supplement administration can maintain and improve mobility, flexibility, and agility throughout your pup’s lifetime.
Helps Reduce
- Supports healthy joint function & flexibility
- Supports Joint and connective tissue structure
- Reduces pain and Inflammation
- Decreases stiffness & discomfort by promoting joint cushioning & lubrication
- Provides powerful antioxidant protection
- May improve athletic performance & recovery
PupFlex+ is formulated with clinically proven ingredients. Learn more about the science behind these ingredients here.
Your Dog’s Joint Transformation Timeline
“Our ten year old lab mix was showing signs of stiffness in her left shoulder, along with some weakness and shaking. After reading about your product, we were excited to give it a try! Your insert said to give it 3 weeks to perhaps see some noticeable difference, but we saw changes in her gait, etc. during the first week. We had been giving her Cosequin with no results at all. Plus, she loves the taste and gobbles them up. Thank you so much for giving us our girl back! ❤️ ”


The Ingredient Science Revolution Your Dog's Joints Have been Waiting For
The 'Old School' Problem:
The PupFlex+ Solution:









Think of this as your dog's joint "reset button"
- Works with your dog's immune system to to help protect and restore cartilage
- Clinically proven over 50% more effective than glucosamine & chondroitin
- Helps restore joint cushioning for free range of motion
- 29 times more bioavailable than other curcumin extracts
- Supports normal inflammatory response in the joints
- Promotes joint comfort & flexibility
- A source of highly bioavailable Omega-3 fatty acids DHA & EPA
- Supports healthy inflammatory response and overall health
- Helps reduce joint stiffness & discomfort
- Shown to reduce joint discomfort in 5 days in human clinical trials
- Supports structural integrity of joints and connective tissue
- Can help protect against the degradation of collagen, which is an important component of joint cartilage
- Powerful antioxidant- 6000 times stronger than Vitamin C, and 600 times stronger than CoQ10.
- supports joint and muscle health with protection from free radicals and nitrous oxide.
- Beneficial for joints, muscles, eyes, brain and heart health
- May help with athletic performance and recovery
- Cushions and lubricates joints from the inside
- Supports joints' synovial fluid viscosity for easy movement
No Matter
Where Your Dog Is in Life, We Meet Them There
Active Dogs
Senior Dogs
Young Pups
Performance & working dogs
”Duke is obviously feeling better since he started on PupFlex. He runs through the pasture alongside my golf cart, which he was very reluctant to do a short time ago. When I ask him if he wants to go out, his eyes light up and he has a big smile on his face.”


Frequently Asked Questions
Your dog does not get all of the active nutrients they need from their food alone. When we assume they get everything they need from their diet, dogs miss out on additional health benefits that target specific health conditions. They also don’t get antioxidants and anti-inflammatory ingredients, joint support, and more. Aside from being repetitive and flavorless oftentimes, your dog’s food isn’t doing more for them when it comes to their nutrition. Supplements with active ingredients can help dogs absorb more nutrients.
You can start giving your dog supplements when they’re a puppy for preventative care if they’re a working or sport dog to recover, or a senior dog who needs support in their older age. Dogs of all ages benefit from bioavailability with BioPup.
BioPup Canine Functional Joint Health complex?
Osteoarthritis can occur in different parts of your dog’s body: hip joints (hip dysplasia), elbow joints (elbow dysplasia), ankles, knees, and spine. BioFlexine helps keep joints healthy in active and athletic dogs, and it’s beneficial for aging dogs improving their quality of life and freedom of movement. It can also help with post-injury recovery.
Yes! PupFlex+ was reviewed, tested, certified and recommended by veterinarians from a VCPR - Veterinary Client-Patient Relationship organization. Our VetEvaluated seal confirms quality of the product.